PROF. QI-LIN ZHOU

State Key Laboratory of Elemento-

organic Chemistry

Nankai University

Weijin Rd. 94, Tianjin 300071

P. R. CHINA

Phone: 86-22-2350 0011

Fax: 86-22-2350 6177

E-mail: qlzhou@nankai.edu.cn

Research Group URL：

http://skleoc.nankai.edu.cn/lab/team/zhouqlteam/

EDUCATION:

1982-1987     Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences, Shanghai, CHINA. Received Ph.D. degree (with Prof. Yao-Zeng Huang) in December, 1987.

1978-1982     Department of Chemistry, Lanzhou University, Lanzhou, CHINA. Received B. Sc. Degree in June, 1982.

 

 

ACADEMIC CAREER:

1999-             Professor of chemistry, State Key Laboratory of Elemento-organic Chemistry, Nankai University, Tianjin, CHINA.

1996-1999     Professor of chemistry, Institute of Fine Chemicals, East China University of Science and Technology, Shanghai, CHINA.

1994-1996     Postdoctoral associate, Department of Chemistry, Trinity University, Texas, U.S.A. (with professor Michael P. Doyle).

1992-1994     Postdoctoral associate, Institute of Organic Chemistry, Basel University, Basel, SWITZERLAND (with professor Andreas Pfaltz).

1990-1992     Postdoctoral associate, Max-Planck Institute of Polymer Science, Mainz, GERMANY (with professor Klaus Muellen).

1988-1990     Postdoctoral associate, Institute of Fine Chemicals, East China University of Science and Technology, Shanghai, CHINA (with Prof. Zheng-Hua Zhu).

 

 

RESEARCH AREAS:

(1)   The development of new synthetic methods.

(2)   Organometallic chemistry directed towards organic synthesis.

(3)   Asymmetric catalysis.

(4)   Synthesis of biologically active natural and unnatural products.

 

 

HONORS AND AWARDS

1997      Award of National Outstanding Young Scientist (National Natural Science Foundation of China)

1999      Yangtze Scholar (Ministry of Education of China)

2005      Prize for Creation in Organic Synthesis (Chinese Chemical Society, Division of Organic Chemistry)

 

 

SELECTED PUBLICATIONS:

1          Xu Cheng, Qi Zhang, Jian-Hua Xie, Li-Xin Wang, Qi-Lin Zhou, Highly rigid diphosphine ligands with large dihedral angle based on chiral spirobifluorene backbone, Angew. Chem. Int. Ed. 2005, 44, 1118-1121.

2          Jian-Hua Xie, Sheng Liu, Xiang-Hong Huo, Xu Cheng, Hai-Feng Duan, Bao-Ming Fan, Li-Xin Wang, Qi-Lin Zhou, Ru(II)-SDP-complexes catalyzed asymmetric hydrogenation of ketones. The effect of alkali metal cation in the reaction, J. Org. Chem. 2005, 70, 2967-2973.

3          Wei Zhang, Li-Xin Wang, Wen-Jian Shi, Qi-Lin Zhou, Copper-catalyzed asymmetric ring opening of oxabicyclic alkenes with Grignard reagents, J. Org. Chem. 2005, 70, 3734-3736.

4          Bao-Min Fan, Jian-Hua Xie, Shen Li, Yong-Qiang Tu, Qi-Lin Zhou, Rhodium-catalyzed asymmetric Pauson-Khand reaction using monophosphoramidite ligand SIPHOS, Adv. Synth. Catal. 2005, 347, 759-762.

5          Shou-Fei Zhu, Yun Yang, Li-Xin Wang, Bin Liu, Qi-Lin Zhou, Synthesis and application of chiral spiro phospholane ligand in Pd-catalyzed asymmetric allylation of aldehydes with allylic alcohols, Org. Lett. 2005, 7, 2333-2335.

6          Jian-Hua Xie, Hai-Feng Duan, Bao-Min Fan, Xu Cheng, Li-Xin Wang, Qi-Lin Zhou, The application of SDP ligands for Pd-catalyzed allylic alkylation, Adv. Synth. Catal. 2004, 346, 625-632.

7          Yu Fu, Xun-Xiang Guo, Shou-Fei Zhu, Ai-Guo Hu, Jian-Hua Xie, Qi-Lin Zhou, Rhodium-catalyzed asymmetric hydrogenation of functionalized olefins using monodentate spiro phosphoramidite ligands, J. Org. Chem. 2004, 69, 4648-4655.

8          Ai-E Wang, Jun Zhong, Jian-Hua Xie, Kai Li, Qi-Lin Zhou, Highly efficient Suzuki cross-coupling catalyzed by palladium/phosphine-imidazolium carbene system, Adv. Synth. Catal. 2004, 346, 595-598.

9          Xu Cheng, Guo-Hua Hou, Jian-Hua Xie, Qi-Lin Zhou, Synthesis and optical resolution of 9,9′-spirobifluorene-1,1′-diol, Org. Lett. 2004, 6, 2381-2383.

10      Yu Fu, Guo-Hua Hou, Jian-Hua Xie, Liang Xing, Li-Xin Wang, Qi-Lin Zhou, Synthesis of monodentate chiral spiro phosphonites and the electronic effect of ligand in asymmetric hydrogenation, J. Org. Chem. 2004, 69, 8157-8160.

11      Hai Zhou, Wen-Hu Wang, Yu Fu, Jian-Hua Xie, Wen-Jian Shi, Li-Xin Wang, and Qi-Lin Zhou, Highly enantioselective copper-catalyzed conjugate addition of diethylzinc to enones using chiral spiro phosphoramidites as ligands, J. Org. Chem. 2003, 68, 1582-1584.

12      Jian-Hua Xie, Li-Xin Wang, Shuo-Fei Zhu, Yu Fu, Bao-Min Fan, Hai-Feng Duan and Qi-Lin Zhou, Synthesis of spiro diphosphine ligands and their application in asymmetric hydrogenation of ketones, J. Am. Chem. Soc. 2003, 125, 4404-4405.

13      Yu Fu, Jian-Hua Xie, Ai-Guo Hu, Hai Zhou, Li-Xin Wang and Qi-Lin Zhou, Novel monodentate spiro phosphorus ligands for rhodium-catalyzed hydrogenation reactions, Chem. Commun. 2002, 480-481.

14      Ai-Guo Hu, Yu Fu, Jian-Hua Xie, Hai Zhou, Li-Xin Wang, and Qi-Lin Zhou, Monodentate chiral spiro phosphoramidites: Efficient ligands for rhodium-catalyzed enantioselective hydrogenation of enamides, Angew. Chem. Int. Ed. 2002, 41, 2348-2350.